Translocation of charged particles through a thin micropore under pressure-driven flow

Junsang Moon, Chang Woo Song, Chang Soo Han

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


We report the effects of a particle surface charge during translocation through a thin micropore based on the simulation and experiments. The translocation of carboxylated and nonfunctionalized polystyrene beads through a fabricated micropore was measured. To compare the translocation behaviors of a particle with/without surface charge under the same driving force, we used a pressure-driven method low bias voltage. We then analyzed the signals with two factors: the translocation time and blocking current. Based on the analysis, we found that, at a low flow rate, the translocation time was largely dependent on the surface charge of the particles. More importantly, we found an unusual phenomenon that the flow rate can affect the blocking current, and the level of effect was significantly determined by the particle’s surface charge. To understand this phenomenon, we suggest a plausible mechanism considering the effect of the convective flow on the counterion flux and FEM results.

Original languageEnglish
Pages (from-to)5181-5189
Number of pages9
JournalJournal of Mechanical Science and Technology
Issue number10
Publication statusPublished - 2022 Oct

Bibliographical note

Funding Information:
This work was supported by the Basic Science Research Program (2021R1A2B5B03001811), STEAM Program (2022 M3C1A3081178) and ERC program (2016M3D1A1952991) through the National Research Foundation, funded by the Ministry of Science and ICT, Korea.

Publisher Copyright:
© 2022, The Korean Society of Mechanical Engineers and Springer-Verlag GmbH Germany, part of Springer Nature.


  • Blocking current
  • Micropore
  • Particle translocation
  • Pressure-driven
  • Surface charge

ASJC Scopus subject areas

  • Mechanics of Materials
  • Mechanical Engineering


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