Treatment of ranula in pediatric patients with intralesional injection of OK-432

Heung Man Lee; Hyun Woo Lim; Hee Joon Kang; Sung Won Chae; Soon Jae Hwang; Kwang Yoon Jung; Jeong Soo Woo

doi:10.1097/01.Mlg.0000216809.90196.83

Treatment of ranula in pediatric patients with intralesional injection of OK-432

Heung Man Lee, Hyun Woo Lim, Hee Joon Kang, Sung Won Chae, Soon Jae Hwang, Kwang Yoon Jung, Jeong Soo Woo

Department of Biomedical Sciences

Research output: Contribution to journal › Review article › peer-review

21 Citations (Scopus)

Abstract

OBJECTIVE: To assess the efficacy of treatment of a ranula in children by intralesional injection of OK-432. STUDY DESIGN:: Retrospective analysis of 13 cases. METHODS: Review of medical records of pediatric patients with ranula treated by OK-432 sclerotherapy from 2002 through 2005. RESULTS: Among 13 cases, 9 were completely regressed by injection therapy alone. Three cases were incompletely regressed. One case was cured by surgical excision. The follow-up duration was 6 to 46 (mean 24.3) months. Adverse effects of OK-432 injection were tolerable, and no complication was observed. CONCLUSIONS: On the basis of our experience, sclerotherapy with OK-432 was a safe and effective primary treatment for a ranula in children. Further study will be needed to conclude its long-term effectiveness.

Original language	English
Pages (from-to)	966-969
Number of pages	4
Journal	Laryngoscope
Volume	116
Issue number	6
DOIs	https://doi.org/10.1097/01.Mlg.0000216809.90196.83
Publication status	Published - 2006 Jun

Keywords

Children
OK-432
Ranula

ASJC Scopus subject areas

Otorhinolaryngology

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10.1097/01.Mlg.0000216809.90196.83

Cite this

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title = "Treatment of ranula in pediatric patients with intralesional injection of OK-432",

abstract = "OBJECTIVE: To assess the efficacy of treatment of a ranula in children by intralesional injection of OK-432. STUDY DESIGN:: Retrospective analysis of 13 cases. METHODS: Review of medical records of pediatric patients with ranula treated by OK-432 sclerotherapy from 2002 through 2005. RESULTS: Among 13 cases, 9 were completely regressed by injection therapy alone. Three cases were incompletely regressed. One case was cured by surgical excision. The follow-up duration was 6 to 46 (mean 24.3) months. Adverse effects of OK-432 injection were tolerable, and no complication was observed. CONCLUSIONS: On the basis of our experience, sclerotherapy with OK-432 was a safe and effective primary treatment for a ranula in children. Further study will be needed to conclude its long-term effectiveness.",

keywords = "Children, OK-432, Ranula",

author = "Lee, {Heung Man} and Lim, {Hyun Woo} and Kang, {Hee Joon} and Chae, {Sung Won} and Hwang, {Soon Jae} and Jung, {Kwang Yoon} and Woo, {Jeong Soo}",

year = "2006",

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doi = "10.1097/01.Mlg.0000216809.90196.83",

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volume = "116",

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journal = "Laryngoscope",

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publisher = "John Wiley and Sons Inc.",

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T1 - Treatment of ranula in pediatric patients with intralesional injection of OK-432

AU - Lee, Heung Man

AU - Lim, Hyun Woo

AU - Kang, Hee Joon

AU - Chae, Sung Won

AU - Hwang, Soon Jae

AU - Jung, Kwang Yoon

AU - Woo, Jeong Soo

PY - 2006/6

Y1 - 2006/6

N2 - OBJECTIVE: To assess the efficacy of treatment of a ranula in children by intralesional injection of OK-432. STUDY DESIGN:: Retrospective analysis of 13 cases. METHODS: Review of medical records of pediatric patients with ranula treated by OK-432 sclerotherapy from 2002 through 2005. RESULTS: Among 13 cases, 9 were completely regressed by injection therapy alone. Three cases were incompletely regressed. One case was cured by surgical excision. The follow-up duration was 6 to 46 (mean 24.3) months. Adverse effects of OK-432 injection were tolerable, and no complication was observed. CONCLUSIONS: On the basis of our experience, sclerotherapy with OK-432 was a safe and effective primary treatment for a ranula in children. Further study will be needed to conclude its long-term effectiveness.

AB - OBJECTIVE: To assess the efficacy of treatment of a ranula in children by intralesional injection of OK-432. STUDY DESIGN:: Retrospective analysis of 13 cases. METHODS: Review of medical records of pediatric patients with ranula treated by OK-432 sclerotherapy from 2002 through 2005. RESULTS: Among 13 cases, 9 were completely regressed by injection therapy alone. Three cases were incompletely regressed. One case was cured by surgical excision. The follow-up duration was 6 to 46 (mean 24.3) months. Adverse effects of OK-432 injection were tolerable, and no complication was observed. CONCLUSIONS: On the basis of our experience, sclerotherapy with OK-432 was a safe and effective primary treatment for a ranula in children. Further study will be needed to conclude its long-term effectiveness.

KW - Children

KW - OK-432

KW - Ranula

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Treatment of ranula in pediatric patients with intralesional injection of OK-432

Abstract

Keywords

ASJC Scopus subject areas

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