Abstract
This study investigates and compares the microstructure, biocompatibility, and tribological properties of two different Ti-based composites, Ti. -10W and Ti. -7.5TiC. -7.5W, with those of pure Ti for their potential use in biomedical applications. In particular, cold and hot isostatic-pressing and arc-melting methods were utilized and compared for the microstructure of the composites. Nano-scratch measurements and pin-on-disk wear tests were employed to understand their tribological behavior. As compared to pure Ti, Ti. -10W and Ti. -7.5TiC. -7.5W showed significantly improved nano-scratch resistance (by 85 and 77%, respectively) and wear resistance (by 64 and 66%, respectively), in good agreement with hardness measurements. For biocompatibility examination, both microculture tetrazolium test (MTT) and water soluble tetrazolium (WST-1) test were used to quantify the cell viability of human osteoblasts and mouse fibroblasts on the materials. Both of the Ti-based composites showed acceptable biocompatibility in comparison with the pure Ti control.
Original language | English |
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Pages (from-to) | 214-222 |
Number of pages | 9 |
Journal | Journal of the Mechanical Behavior of Biomedical Materials |
Volume | 30 |
DOIs | |
Publication status | Published - 2014 Feb |
Keywords
- Biocompatibility
- Cell proliferation
- Titanium
- Wear mechanism
ASJC Scopus subject areas
- Biomaterials
- Biomedical Engineering
- Mechanics of Materials