Two cases of Plasmodium vivax malaria with the clinical picture resembling toxic shock

Young Song Joon; Won Park Cheong; Mee Jo You; Yun Kim Jeong; Hyun Kim Jeong; Joong Yoon Hyo; Hoon Kim Chi; Seung Lim Chae; Jin Cheong Hee; Joo Kim Woo

doi:10.4269/ajtmh.2007.77.609

Two cases of Plasmodium vivax malaria with the clinical picture resembling toxic shock

Young Song Joon, Won Park Cheong, Mee Jo You, Yun Kim Jeong, Hyun Kim Jeong, Joong Yoon Hyo, Hoon Kim Chi, Seung Lim Chae, Jin Cheong Hee, Joo Kim Woo

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

Fatal complications of Plasmodium falciparum malaria have been reported. However, complicated P. vivax malaria is rare. We observed two unusual cases of P. vivax malaria who presented with clinical pictures of toxic shock. Both showed disseminated intravascular coagulation with marked thrombocytopenia, oliguric renal failure, and pulmonary edema. Examination of initial blood smears showed a P. vivax parasitemia of 2,352/μL and 12,376/μL, respectively. The patients were treated with hydroxychloroquine and primaquine without an antibacterial agent. These cases emphasize the importance of considering the possibility of P. vivax malarial infection in patients with a clinical picture resembling toxic shock if they have a travel history to malaria-endemic areas.

Original language	English
Pages (from-to)	609-611
Number of pages	3
Journal	American Journal of Tropical Medicine and Hygiene
Volume	77
Issue number	4
DOIs	https://doi.org/10.4269/ajtmh.2007.77.609
Publication status	Published - 2007 Oct

ASJC Scopus subject areas

Parasitology
Virology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.4269/ajtmh.2007.77.609

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title = "Two cases of Plasmodium vivax malaria with the clinical picture resembling toxic shock",

abstract = "Fatal complications of Plasmodium falciparum malaria have been reported. However, complicated P. vivax malaria is rare. We observed two unusual cases of P. vivax malaria who presented with clinical pictures of toxic shock. Both showed disseminated intravascular coagulation with marked thrombocytopenia, oliguric renal failure, and pulmonary edema. Examination of initial blood smears showed a P. vivax parasitemia of 2,352/μL and 12,376/μL, respectively. The patients were treated with hydroxychloroquine and primaquine without an antibacterial agent. These cases emphasize the importance of considering the possibility of P. vivax malarial infection in patients with a clinical picture resembling toxic shock if they have a travel history to malaria-endemic areas.",

author = "Joon, {Young Song} and Cheong, {Won Park} and You, {Mee Jo} and Jeong, {Yun Kim} and Jeong, {Hyun Kim} and Hyo, {Joong Yoon} and Chi, {Hoon Kim} and Chae, {Seung Lim} and Hee, {Jin Cheong} and Woo, {Joo Kim}",

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AU - Joon, Young Song

AU - Cheong, Won Park

AU - You, Mee Jo

AU - Jeong, Yun Kim

AU - Jeong, Hyun Kim

AU - Hyo, Joong Yoon

AU - Chi, Hoon Kim

AU - Chae, Seung Lim

AU - Hee, Jin Cheong

AU - Woo, Joo Kim

PY - 2007/10

Y1 - 2007/10

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AB - Fatal complications of Plasmodium falciparum malaria have been reported. However, complicated P. vivax malaria is rare. We observed two unusual cases of P. vivax malaria who presented with clinical pictures of toxic shock. Both showed disseminated intravascular coagulation with marked thrombocytopenia, oliguric renal failure, and pulmonary edema. Examination of initial blood smears showed a P. vivax parasitemia of 2,352/μL and 12,376/μL, respectively. The patients were treated with hydroxychloroquine and primaquine without an antibacterial agent. These cases emphasize the importance of considering the possibility of P. vivax malarial infection in patients with a clinical picture resembling toxic shock if they have a travel history to malaria-endemic areas.

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Two cases of Plasmodium vivax malaria with the clinical picture resembling toxic shock

Abstract

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