Two distinct forms of human BLT2: long-form and short-form BLT2

Jun Dong Wei, Jae Hong Kim

Research output: Contribution to journalShort surveypeer-review

Abstract

BLT2 is a low-affinity leukotriene B4 receptor that plays an essential role in the pathogenesis of various inflammatory diseases, including asthma and cancer. BLT2 is minimally expressed in a normal internal environment but is overexpressed in a stress-induced inflammatory environment. Recent research indicated that human BLT2 has two distinct forms. Although their functions are likely to be different, very few studies investigated these differences. Therefore, this paper will discuss about the two distinct forms of human BLT2; the short-form of BLT2 and the long-form of BLT2.

Original languageEnglish
Article number1288373
JournalFrontiers in Cell and Developmental Biology
Volume11
DOIs
Publication statusPublished - 2023

Bibliographical note

Publisher Copyright:
Copyright © 2023 Wei and Kim.

Keywords

  • BLT2
  • G protein-coupled receptor
  • leukotriene B
  • lipid mediator
  • N-terminal domain

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

Fingerprint

Dive into the research topics of 'Two distinct forms of human BLT2: long-form and short-form BLT2'. Together they form a unique fingerprint.

Cite this