Two 1,3-calixazacrowns-5 in the 1,3-alternate conformation have been constructed from calixarene. They formed 1:1 endo and 1:2 endo-endo complexes with NH4+ in CDCl3. Comparison with 1,3-calix-bis-crown-5 lead us to conclude a better binding by replacement of the central O atom by NH group in the crown. (C) 2000 Elsevier Science Ltd.
Bibliographical noteFunding Information:
This research was fully supported by the Korea Research Foundation (BSRI Grant No. 1999-015-DP0203).
Copyright 2004 Elsevier Science B.V., Amsterdam. All rights reserved.
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry