Abstract
The living image: The efficient two-photon probes AZn1 and AZn2 (see picture for rat brain tissue) show 24-to 52-fold two-photon excited fluorescence enhancement in response to Zn2+. They can selectively detect intracellular free Zn2+ ions in live cells and in living tissues at a depth of 80-150 mm without interference from other metal ions and the membrane-bound probes. (Chemical Equation Presented)
Original language | English |
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Pages (from-to) | 5167-5170 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 47 |
Issue number | 28 |
DOIs | |
Publication status | Published - 2008 Jun 27 |
Keywords
- Fluorescent probes
- Imaging agents
- Living tissue
- Two-photon microscopy
- Zinc
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)