Two-photon fluorescent probes for metal ions in live tissues

Avik Ranjan Sarkar; Dong Eun Kang; Hwan Myung Kim; Bong Rae Cho

doi:10.1021/ic402475f

Two-photon fluorescent probes for metal ions in live tissues

Avik Ranjan Sarkar, Dong Eun Kang, Hwan Myung Kim, Bong Rae Cho

Research output: Contribution to journal › Review article › peer-review

73 Citations (Scopus)

Abstract

Two-photon microscopy (TPM) is a new imaging tool that can detect biological targets deep inside a live tissue. To faciltate the use of TPM in biomedical research, a variety of two-photon (TP) probes for specific applications are needed. In this Forum Article, we describe the design strategy, photophysical properties, and biological imaging applications of a selection of our recent studies in the development of TP probes for metal ions. Small-molecule TP turn-on probes, organelle-targeted probes, and multicolor emissive probes for dual-color imaging are briefly reviewed.

Original language	English
Pages (from-to)	1794-1803
Number of pages	10
Journal	Inorganic Chemistry
Volume	53
Issue number	4
DOIs	https://doi.org/10.1021/ic402475f
Publication status	Published - 2014 Feb 17

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Inorganic Chemistry

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10.1021/ic402475f

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abstract = "Two-photon microscopy (TPM) is a new imaging tool that can detect biological targets deep inside a live tissue. To faciltate the use of TPM in biomedical research, a variety of two-photon (TP) probes for specific applications are needed. In this Forum Article, we describe the design strategy, photophysical properties, and biological imaging applications of a selection of our recent studies in the development of TP probes for metal ions. Small-molecule TP turn-on probes, organelle-targeted probes, and multicolor emissive probes for dual-color imaging are briefly reviewed.",

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AU - Sarkar, Avik Ranjan

AU - Kang, Dong Eun

AU - Kim, Hwan Myung

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Y1 - 2014/2/17

N2 - Two-photon microscopy (TPM) is a new imaging tool that can detect biological targets deep inside a live tissue. To faciltate the use of TPM in biomedical research, a variety of two-photon (TP) probes for specific applications are needed. In this Forum Article, we describe the design strategy, photophysical properties, and biological imaging applications of a selection of our recent studies in the development of TP probes for metal ions. Small-molecule TP turn-on probes, organelle-targeted probes, and multicolor emissive probes for dual-color imaging are briefly reviewed.

AB - Two-photon microscopy (TPM) is a new imaging tool that can detect biological targets deep inside a live tissue. To faciltate the use of TPM in biomedical research, a variety of two-photon (TP) probes for specific applications are needed. In this Forum Article, we describe the design strategy, photophysical properties, and biological imaging applications of a selection of our recent studies in the development of TP probes for metal ions. Small-molecule TP turn-on probes, organelle-targeted probes, and multicolor emissive probes for dual-color imaging are briefly reviewed.

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Two-photon fluorescent probes for metal ions in live tissues

Abstract

ASJC Scopus subject areas

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