Two-photon fluorescent probes for metal ions in live tissues

Avik Ranjan Sarkar, Dong Eun Kang, Hwan Myung Kim, Bong Rae Cho

Research output: Contribution to journalReview articlepeer-review

69 Citations (Scopus)


Two-photon microscopy (TPM) is a new imaging tool that can detect biological targets deep inside a live tissue. To faciltate the use of TPM in biomedical research, a variety of two-photon (TP) probes for specific applications are needed. In this Forum Article, we describe the design strategy, photophysical properties, and biological imaging applications of a selection of our recent studies in the development of TP probes for metal ions. Small-molecule TP turn-on probes, organelle-targeted probes, and multicolor emissive probes for dual-color imaging are briefly reviewed.

Original languageEnglish
Pages (from-to)1794-1803
Number of pages10
JournalInorganic Chemistry
Issue number4
Publication statusPublished - 2014 Feb 17

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry


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