Two-photon lysotrackers for in vivo imaging

Ji Hoon Son, Chang Su Lim, Ji Hee Han, Isravel Antony Danish, Hwan Myung Kim, Bong Rae Cho

    Research output: Contribution to journalArticlepeer-review

    45 Citations (Scopus)

    Abstract

    We report two-photon Lysotrackers (CLT-blue and CLT-yellow) that can be excited by 750-840 nm femtosecond laser pulses and emit at 470 and 550 nm, respectively. They can be easily loaded into cells and tissue slices for visualization of lysosomes in live cells and tissues for a long period of time through two-photon microscopy. When combined with appropriate two-photon probes for other biological targets, these novel probes would greatly facilitate the two-photon microscopy colocalization experiments. (Figure presented)

    Original languageEnglish
    Pages (from-to)8113-8116
    Number of pages4
    JournalJournal of Organic Chemistry
    Volume76
    Issue number19
    DOIs
    Publication statusPublished - 2011 Oct 7

    ASJC Scopus subject areas

    • Organic Chemistry

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