Abstract
We report two-photon Lysotrackers (CLT-blue and CLT-yellow) that can be excited by 750-840 nm femtosecond laser pulses and emit at 470 and 550 nm, respectively. They can be easily loaded into cells and tissue slices for visualization of lysosomes in live cells and tissues for a long period of time through two-photon microscopy. When combined with appropriate two-photon probes for other biological targets, these novel probes would greatly facilitate the two-photon microscopy colocalization experiments. (Figure presented)
Original language | English |
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Pages (from-to) | 8113-8116 |
Number of pages | 4 |
Journal | Journal of Organic Chemistry |
Volume | 76 |
Issue number | 19 |
DOIs | |
Publication status | Published - 2011 Oct 7 |
ASJC Scopus subject areas
- Organic Chemistry