Ultra-sensitive direct detection of silver ions via Kelvin probe force microscopy

Jinsung Park; Sangmyung Lee; Kuewhan Jang; Sungsoo Na

doi:10.1016/j.bios.2014.04.038

Ultra-sensitive direct detection of silver ions via Kelvin probe force microscopy

Jinsung Park, Sangmyung Lee, Kuewhan Jang, Sungsoo Na

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

Nanotoxicity is receiving great importance due to its potential impact on human health and environment and due to rapid development in the field of nanoscale research and industry. Herein, we report the Kelvin probe force microscope (KPPM)-based nanotoxicity material detection using surface potential difference. In general, it is difficult to measure the size of ion (Ag⁺) using a conventional atomic force microscope (AFM) because of the limited resolution. In this study, we have demonstrated that KPFM is capable of ultra-sensitive detection of silver ion with silver specific DNA by a single droplet. Furthermore, the measured surface potentials for Ag+ and DNA binding enable the detection performance for a practical sample that is general drinking water. Remarkably, the KPFM based silver ion detection enables an insight into the coordination chemistry, which plays an important role in early detection of toxicity. This implies that KPFM based detection system opens a new avenue for water testing sensor.

Original language	English
Pages (from-to)	299-304
Number of pages	6
Journal	Biosensors and Bioelectronics
Volume	60
DOIs	https://doi.org/10.1016/j.bios.2014.04.038
Publication status	Published - 2014 Oct 15

Bibliographical note

Funding Information:
This research was supported by the National Research Foundation of Korea (NRF) under Grant nos. NRF-2013-044213 , ERC-2007-0056094 , and NRF-2013058102 which is funded by the Ministry of Science, ICT & Future Planning.

Keywords

DNA-metal interaction
Kelvin probe force microscope
Silver ion
Single droplet
Surface potential

ASJC Scopus subject areas

Biotechnology
Biophysics
Biomedical Engineering
Electrochemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.bios.2014.04.038

Cite this

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title = "Ultra-sensitive direct detection of silver ions via Kelvin probe force microscopy",

abstract = "Nanotoxicity is receiving great importance due to its potential impact on human health and environment and due to rapid development in the field of nanoscale research and industry. Herein, we report the Kelvin probe force microscope (KPPM)-based nanotoxicity material detection using surface potential difference. In general, it is difficult to measure the size of ion (Ag+) using a conventional atomic force microscope (AFM) because of the limited resolution. In this study, we have demonstrated that KPFM is capable of ultra-sensitive detection of silver ion with silver specific DNA by a single droplet. Furthermore, the measured surface potentials for Ag+ and DNA binding enable the detection performance for a practical sample that is general drinking water. Remarkably, the KPFM based silver ion detection enables an insight into the coordination chemistry, which plays an important role in early detection of toxicity. This implies that KPFM based detection system opens a new avenue for water testing sensor.",

keywords = "DNA-metal interaction, Kelvin probe force microscope, Silver ion, Single droplet, Surface potential",

author = "Jinsung Park and Sangmyung Lee and Kuewhan Jang and Sungsoo Na",

note = "Funding Information: This research was supported by the National Research Foundation of Korea (NRF) under Grant nos. NRF-2013-044213 , ERC-2007-0056094 , and NRF-2013058102 which is funded by the Ministry of Science, ICT & Future Planning. ",

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doi = "10.1016/j.bios.2014.04.038",

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AU - Park, Jinsung

AU - Lee, Sangmyung

AU - Jang, Kuewhan

AU - Na, Sungsoo

N1 - Funding Information: This research was supported by the National Research Foundation of Korea (NRF) under Grant nos. NRF-2013-044213 , ERC-2007-0056094 , and NRF-2013058102 which is funded by the Ministry of Science, ICT & Future Planning.

PY - 2014/10/15

Y1 - 2014/10/15

N2 - Nanotoxicity is receiving great importance due to its potential impact on human health and environment and due to rapid development in the field of nanoscale research and industry. Herein, we report the Kelvin probe force microscope (KPPM)-based nanotoxicity material detection using surface potential difference. In general, it is difficult to measure the size of ion (Ag+) using a conventional atomic force microscope (AFM) because of the limited resolution. In this study, we have demonstrated that KPFM is capable of ultra-sensitive detection of silver ion with silver specific DNA by a single droplet. Furthermore, the measured surface potentials for Ag+ and DNA binding enable the detection performance for a practical sample that is general drinking water. Remarkably, the KPFM based silver ion detection enables an insight into the coordination chemistry, which plays an important role in early detection of toxicity. This implies that KPFM based detection system opens a new avenue for water testing sensor.

AB - Nanotoxicity is receiving great importance due to its potential impact on human health and environment and due to rapid development in the field of nanoscale research and industry. Herein, we report the Kelvin probe force microscope (KPPM)-based nanotoxicity material detection using surface potential difference. In general, it is difficult to measure the size of ion (Ag+) using a conventional atomic force microscope (AFM) because of the limited resolution. In this study, we have demonstrated that KPFM is capable of ultra-sensitive detection of silver ion with silver specific DNA by a single droplet. Furthermore, the measured surface potentials for Ag+ and DNA binding enable the detection performance for a practical sample that is general drinking water. Remarkably, the KPFM based silver ion detection enables an insight into the coordination chemistry, which plays an important role in early detection of toxicity. This implies that KPFM based detection system opens a new avenue for water testing sensor.

KW - DNA-metal interaction

KW - Kelvin probe force microscope

KW - Silver ion

KW - Single droplet

KW - Surface potential

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ER -

Ultra-sensitive direct detection of silver ions via Kelvin probe force microscopy

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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