TY - GEN
T1 - Unconverted double bonds in the hydrogel network synthesized via flow lithography
AU - Moon, Hyun June
AU - Ku, Minhee
AU - Lee, Hyunjee
AU - Yang, Jaemoon
AU - Bong, Ki Wan
N1 - Funding Information:
This work was supported by the National Research Foundation of Korea (NRF-2016R1A5A1010148, ERC).
Publisher Copyright:
© 17CBMS-0001.
PY - 2020
Y1 - 2020
N2 - Flow lithography, a versatile technique to synthesize anisotropic multifunctional microparticles, generates hydrogel networks containing a considerable number of unconverted double bonds. These unconverted pendant groups are highly reactive, potentially bringing physicochemical changes in particles and pernicious effects to biological systems. Herein, we validate that the hydrogel networks synthesized via flow lithography bear unconverted double bonds and present a simple method that can be used to eliminate the unconverted double bonds based on thiol-ene click chemistry.
AB - Flow lithography, a versatile technique to synthesize anisotropic multifunctional microparticles, generates hydrogel networks containing a considerable number of unconverted double bonds. These unconverted pendant groups are highly reactive, potentially bringing physicochemical changes in particles and pernicious effects to biological systems. Herein, we validate that the hydrogel networks synthesized via flow lithography bear unconverted double bonds and present a simple method that can be used to eliminate the unconverted double bonds based on thiol-ene click chemistry.
KW - Biochemically inert particles
KW - Cross-linked networks
KW - Flow lithography
KW - Thiol-ene click chemistry
UR - http://www.scopus.com/inward/record.url?scp=85079638429&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85079638429
T3 - 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
SP - 338
EP - 339
BT - 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
PB - Chemical and Biological Microsystems Society
T2 - 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
Y2 - 22 October 2017 through 26 October 2017
ER -