Unconverted double bonds in the hydrogel network synthesized via flow lithography

Hyun June Moon, Minhee Ku, Hyunjee Lee, Jaemoon Yang, Ki Wan Bong

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    Flow lithography, a versatile technique to synthesize anisotropic multifunctional microparticles, generates hydrogel networks containing a considerable number of unconverted double bonds. These unconverted pendant groups are highly reactive, potentially bringing physicochemical changes in particles and pernicious effects to biological systems. Herein, we validate that the hydrogel networks synthesized via flow lithography bear unconverted double bonds and present a simple method that can be used to eliminate the unconverted double bonds based on thiol-ene click chemistry.

    Original languageEnglish
    Title of host publication21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
    PublisherChemical and Biological Microsystems Society
    Pages338-339
    Number of pages2
    ISBN (Electronic)9780692941836
    Publication statusPublished - 2020
    Event21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States
    Duration: 2017 Oct 222017 Oct 26

    Publication series

    Name21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

    Conference

    Conference21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
    Country/TerritoryUnited States
    CitySavannah
    Period17/10/2217/10/26

    Bibliographical note

    Funding Information:
    This work was supported by the National Research Foundation of Korea (NRF-2016R1A5A1010148, ERC).

    Publisher Copyright:
    © 17CBMS-0001.

    Keywords

    • Biochemically inert particles
    • Cross-linked networks
    • Flow lithography
    • Thiol-ene click chemistry

    ASJC Scopus subject areas

    • Chemical Engineering (miscellaneous)
    • Bioengineering

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