Use of hepatobiliary phase images in Gd-EOB-DTPA-enhanced MRI of breast cancer hepatic metastasis to predict response to chemotherapy

Hyun Ji Lee; Chang Hee Lee; Jeong Woo Kim; Yang Shin Park; Jongmee Lee; Kyeong Ah Kim

doi:10.1016/j.clinimag.2017.03.005

Use of hepatobiliary phase images in Gd-EOB-DTPA-enhanced MRI of breast cancer hepatic metastasis to predict response to chemotherapy

Hyun Ji Lee
, Chang Hee Lee^*
, Jeong Woo Kim
, Yang Shin Park
, Jongmee Lee
, Kyeong Ah Kim

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Objectives To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis from breast cancer. Methods 29 metastatic lesions from 12 breast cancer patients who received chemotherapy were retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified them as a “target” or “non-target” appearance. The relationship of appearance or SI ratio with tumor response was analyzed. Results A non-target appearance was more frequent in disease control group than in non-control group [14/18 (77.8%) vs. 4/18 (22.2%)], and it was associated with a better response [p = 0.048]. Conclusion HBP analysis may be useful to predict the response to chemotherapy and survival.

Original language	English
Pages (from-to)	127-131
Number of pages	5
Journal	Clinical Imaging
Volume	43
DOIs	https://doi.org/10.1016/j.clinimag.2017.03.005
Publication status	Published - 2017 May 1
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2017 Elsevier Inc.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Breast cancer liver metastases
Chemotherapy response
Gadoxetic acid
Hepatobiliary phase (HBP)
MRI

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1016/j.clinimag.2017.03.005

Cite this

@article{539bde2838e244d3b1e2a1bab63d664a,

title = "Use of hepatobiliary phase images in Gd-EOB-DTPA-enhanced MRI of breast cancer hepatic metastasis to predict response to chemotherapy",

abstract = "Objectives To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis from breast cancer. Methods 29 metastatic lesions from 12 breast cancer patients who received chemotherapy were retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified them as a “target” or “non-target” appearance. The relationship of appearance or SI ratio with tumor response was analyzed. Results A non-target appearance was more frequent in disease control group than in non-control group [14/18 (77.8\%) vs. 4/18 (22.2\%)], and it was associated with a better response [p = 0.048]. Conclusion HBP analysis may be useful to predict the response to chemotherapy and survival.",

keywords = "Breast cancer liver metastases, Chemotherapy response, Gadoxetic acid, Hepatobiliary phase (HBP), MRI",

author = "Lee, \{Hyun Ji\} and Lee, \{Chang Hee\} and Kim, \{Jeong Woo\} and Park, \{Yang Shin\} and Jongmee Lee and Kim, \{Kyeong Ah\}",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Inc.",

year = "2017",

month = may,

day = "1",

doi = "10.1016/j.clinimag.2017.03.005",

language = "English",

volume = "43",

pages = "127--131",

journal = "Clinical Imaging",

issn = "0899-7071",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Use of hepatobiliary phase images in Gd-EOB-DTPA-enhanced MRI of breast cancer hepatic metastasis to predict response to chemotherapy

AU - Lee, Hyun Ji

AU - Lee, Chang Hee

AU - Kim, Jeong Woo

AU - Park, Yang Shin

AU - Lee, Jongmee

AU - Kim, Kyeong Ah

PY - 2017/5/1

Y1 - 2017/5/1

N2 - Objectives To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis from breast cancer. Methods 29 metastatic lesions from 12 breast cancer patients who received chemotherapy were retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified them as a “target” or “non-target” appearance. The relationship of appearance or SI ratio with tumor response was analyzed. Results A non-target appearance was more frequent in disease control group than in non-control group [14/18 (77.8%) vs. 4/18 (22.2%)], and it was associated with a better response [p = 0.048]. Conclusion HBP analysis may be useful to predict the response to chemotherapy and survival.

AB - Objectives To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis from breast cancer. Methods 29 metastatic lesions from 12 breast cancer patients who received chemotherapy were retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified them as a “target” or “non-target” appearance. The relationship of appearance or SI ratio with tumor response was analyzed. Results A non-target appearance was more frequent in disease control group than in non-control group [14/18 (77.8%) vs. 4/18 (22.2%)], and it was associated with a better response [p = 0.048]. Conclusion HBP analysis may be useful to predict the response to chemotherapy and survival.

KW - Breast cancer liver metastases

KW - Chemotherapy response

KW - Gadoxetic acid

KW - Hepatobiliary phase (HBP)

KW - MRI

UR - https://www.scopus.com/pages/publications/85014990382

U2 - 10.1016/j.clinimag.2017.03.005

DO - 10.1016/j.clinimag.2017.03.005

M3 - Article

C2 - 28314197

AN - SCOPUS:85014990382

SN - 0899-7071

VL - 43

SP - 127

EP - 131

JO - Clinical Imaging

JF - Clinical Imaging

ER -

Use of hepatobiliary phase images in Gd-EOB-DTPA-enhanced MRI of breast cancer hepatic metastasis to predict response to chemotherapy

Abstract

Bibliographical note

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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