Use of hydrogen peroxide as an effective disinfectant to Actinobacillus ureae

Ho Hyuk Jang, Sung Ho Ann, Myung Deok Kim, Chan Wha Kim

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Actinobacillus ureae (A. ureae), is a human pathogen readily detected as an environmental isolate. Presently, no vaccine against A. ureae has been developed yet; thus, a host environment cleaning using disinfectants is the most effective way to prevent the pathogen's transmission. The aim of this study is to determine the most effective disinfectant to inhibit A. ureae, directly extracted from the environment using three easily available disinfectants: 3% hydrogen peroxide (3% HP), 70% isopropyl alcohol (70% IA), and synthetic phenol (SP). Results show that A. ureae is resistant to both 70% IA and SP - which are biocidal to ATCC strains (Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, and Aspergillus niger) - in the suspension test. On the other hand, this resistance was not observed with 3% HP. Also in the zone inhibition test, A. ureae is found to be susceptible to 3% HP. Thus, 3% HP showed the most promise for disinfecting A. ureae.

Original languageEnglish
Pages (from-to)225-228
Number of pages4
JournalProcess Biochemistry
Issue number3
Publication statusPublished - 2008 Mar

Bibliographical note

Copyright 2019 Elsevier B.V., All rights reserved.


  • 3% hydrogen peroxide
  • Actinobacillus ureae
  • Disinfectant
  • Environmental isolate
  • Human pathogen

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Applied Microbiology and Biotechnology


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