Utility of tantalum (Ta) coating to improve surface hardness in vitro bioactivity and biocompatibility of Co-Cr

Vuong Hung Pham, Seung Hee Lee, Yuanlong Li, Hyoun Ee Kim, Kwan Ha Shin, Young Hag Koh

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)


This study reports the utility of tantalum (Ta) coating for improving the surface hardness, in vitro bioactivity and biocompatibility of Co-Cr implants. The use of direct current sputtering allowed for the deposition of a dense and uniform Ta film onto a Co-Cr substrate, which was composed of β-phase Ta grains. This hard Ta coating significantly improved the surface hardness of the Co-Cr by a factor of > 2.3. In addition, the Ta-deposited Co-Cr substrate showed a vigorous precipitation of apatite crystals on its surface after 4 weeks of immersion in simulated body fluid, suggesting its excellent in vitro bioactivity. This bioactive Ta coating led to a considerable improvement in the in vitro biocompatibility of the Co-Cr, which was assessed in terms of the attachment, proliferation and differentiation of pre-osteoblasts (MC3T3-E1).

Original languageEnglish
Pages (from-to)269-274
Number of pages6
JournalThin Solid Films
Publication statusPublished - 2013 Jun 1

Bibliographical note

Funding Information:
This research was supported by a grant from the Fundamental R&D Program for Core Technology of Materials funded by the Ministry of Knowledge Economy, Republic of Korea .


  • Biomaterials
  • Co-Cr substrates
  • Cytoskeleton
  • Differentiation
  • Sputtering
  • Tantalum

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


Dive into the research topics of 'Utility of tantalum (Ta) coating to improve surface hardness in vitro bioactivity and biocompatibility of Co-Cr'. Together they form a unique fingerprint.

Cite this