Utility of the cutaneous silent period in patients with diabetes mellitus

Byung Jo Kim, Nan Hee Kim, Sin Gon Kim, Hakjae Roh, Ha Rim Park, Moon Ho Park, Kun Woo Park, S. Charles Cho, Yuen T. So

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


We performed this study to evaluate whether or not the cutaneous silent period (CSP) is a useful metric to identify small-fiber neuropathy in diabetic patients. The CSP was measured from the abductor pollicis brevis muscle in 30 healthy controls and 110 diabetic patients, who in turn were divided into 3 subgroups (patients with large-fiber neuropathy, patients with small-fiber neuropathy, and asymptomatic patients). The measured CSP and clinical characteristics were compared among the groups. The power of the CSP in discriminating patients from controls and any correlation with other clinical variables were analyzed. Each patient subgroup had a significantly delayed CSP latency compared to the controls. The latency of patients with large-fiber neuropathy was also significantly prolonged compared to the other subgroups of patients. The CSP latency was the only variable to discriminate patients. The latency showed a significant correlation with the late responses in nerve conduction studies. Thus, the CSP latency may be a useful tool in evaluating small neural fiber function in diabetic patients.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalJournal of the Neurological Sciences
Issue number1-2
Publication statusPublished - 2010 Jun 15
Externally publishedYes


  • Cutaneous silent period
  • Diabetes mellitus
  • Diabetic polyneuropathy
  • Nerve conduction study
  • Small-fiber neuropathy

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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