Utilization of monolinolein as a substrate for conjugated linoleic acid production by Bifidobacterium breve LMC 520 of human neonatal origin

Jin Choi Nag; Gyu Park Hui; Jun Kim Young; Hwan Kim In; Soon Kang Hye; Suk Yoon Chil; Geun Yoon Ho; Su Il Park; Woo Lee Jae; Hyun Chung Soo

doi:10.1021/jf801597t

Utilization of monolinolein as a substrate for conjugated linoleic acid production by Bifidobacterium breve LMC 520 of human neonatal origin

Jin Choi Nag, Gyu Park Hui, Jun Kim Young, Hwan Kim In, Soon Kang Hye, Suk Yoon Chil, Geun Yoon Ho, Su Il Park, Woo Lee Jae, Hyun Chung Soo

Department of Public Health Sciences

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

This study was designed to isolate bifidobacteria from human intestines that efficiently converts monolinolein, a monoglyceride form of linoleic acid, into conjugated linoleic acid (CLA), as well as to optimize culture conditions for improving CLA production during milk fermentation. Among 150 screened neonatal bifidobacteria, Bifidobacterium breve LMC 520 showed the highest CLA-producing ability and was tested with different types of fat substrates at various concentrations to determine the optimal conditions for CLA production. Monolinolein was tested as a substrate for CLA production. The incubation time optimized for CLA production was 24 h, and CLA production was proportionally increased with monolinolein concentration. The incubation of LMC 520 with commercial starter strains caused minimal reduction in CLA production. Our results demonstrate that the CLA-producing ability of B. breve LMC 520 could offer beneficial effects when utilized as a starter culture for the development of functional dairy products.

Original language	English
Pages (from-to)	10908-10912
Number of pages	5
Journal	Journal of agricultural and food chemistry
Volume	56
Issue number	22
DOIs	https://doi.org/10.1021/jf801597t
Publication status	Published - 2008 Nov 26

Keywords

Bifidobacterium breve
Conjugated linoleic acid
Milk fermentation
Monolinolein
Starter

ASJC Scopus subject areas

Chemistry(all)
Agricultural and Biological Sciences(all)

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10.1021/jf801597t

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Nag, J. C., Hui, G. P., Young, J. K., In, H. K., Hye, S. K., Chil, S. Y., Ho, G. Y., Park, S. I., Jae, W. L., & Soo, H. C. (2008). Utilization of monolinolein as a substrate for conjugated linoleic acid production by Bifidobacterium breve LMC 520 of human neonatal origin. Journal of agricultural and food chemistry, 56(22), 10908-10912. https://doi.org/10.1021/jf801597t

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title = "Utilization of monolinolein as a substrate for conjugated linoleic acid production by Bifidobacterium breve LMC 520 of human neonatal origin",

abstract = "This study was designed to isolate bifidobacteria from human intestines that efficiently converts monolinolein, a monoglyceride form of linoleic acid, into conjugated linoleic acid (CLA), as well as to optimize culture conditions for improving CLA production during milk fermentation. Among 150 screened neonatal bifidobacteria, Bifidobacterium breve LMC 520 showed the highest CLA-producing ability and was tested with different types of fat substrates at various concentrations to determine the optimal conditions for CLA production. Monolinolein was tested as a substrate for CLA production. The incubation time optimized for CLA production was 24 h, and CLA production was proportionally increased with monolinolein concentration. The incubation of LMC 520 with commercial starter strains caused minimal reduction in CLA production. Our results demonstrate that the CLA-producing ability of B. breve LMC 520 could offer beneficial effects when utilized as a starter culture for the development of functional dairy products.",

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author = "Nag, {Jin Choi} and Hui, {Gyu Park} and Young, {Jun Kim} and In, {Hwan Kim} and Hye, {Soon Kang} and Chil, {Suk Yoon} and Ho, {Geun Yoon} and Park, {Su Il} and Jae, {Woo Lee} and Soo, {Hyun Chung}",

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AU - Hui, Gyu Park

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AU - In, Hwan Kim

AU - Hye, Soon Kang

AU - Chil, Suk Yoon

AU - Ho, Geun Yoon

AU - Park, Su Il

AU - Jae, Woo Lee

AU - Soo, Hyun Chung

PY - 2008/11/26

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N2 - This study was designed to isolate bifidobacteria from human intestines that efficiently converts monolinolein, a monoglyceride form of linoleic acid, into conjugated linoleic acid (CLA), as well as to optimize culture conditions for improving CLA production during milk fermentation. Among 150 screened neonatal bifidobacteria, Bifidobacterium breve LMC 520 showed the highest CLA-producing ability and was tested with different types of fat substrates at various concentrations to determine the optimal conditions for CLA production. Monolinolein was tested as a substrate for CLA production. The incubation time optimized for CLA production was 24 h, and CLA production was proportionally increased with monolinolein concentration. The incubation of LMC 520 with commercial starter strains caused minimal reduction in CLA production. Our results demonstrate that the CLA-producing ability of B. breve LMC 520 could offer beneficial effects when utilized as a starter culture for the development of functional dairy products.

AB - This study was designed to isolate bifidobacteria from human intestines that efficiently converts monolinolein, a monoglyceride form of linoleic acid, into conjugated linoleic acid (CLA), as well as to optimize culture conditions for improving CLA production during milk fermentation. Among 150 screened neonatal bifidobacteria, Bifidobacterium breve LMC 520 showed the highest CLA-producing ability and was tested with different types of fat substrates at various concentrations to determine the optimal conditions for CLA production. Monolinolein was tested as a substrate for CLA production. The incubation time optimized for CLA production was 24 h, and CLA production was proportionally increased with monolinolein concentration. The incubation of LMC 520 with commercial starter strains caused minimal reduction in CLA production. Our results demonstrate that the CLA-producing ability of B. breve LMC 520 could offer beneficial effects when utilized as a starter culture for the development of functional dairy products.

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Utilization of monolinolein as a substrate for conjugated linoleic acid production by Bifidobacterium breve LMC 520 of human neonatal origin

Abstract

Keywords

ASJC Scopus subject areas

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