Clear cell sarcoma of the kidney (CCSK) is uncommon pediatric renal tumor and can present a significant therapeutic challenge in those patients whose tumors spread beyond the kidney. Thus, identifying potential novel targets for treatment may be clinically important. Clear cell sarcoma of the kidney is characterized by a unique vascular pattern, in which nests of tumor cells are separated by regularly-spaced, fine fibrovascular septa. This distinctive histopathology raises the possibility that understanding the factors which drive angiogenesis in CCSK tumors may suggest new therapeutic targets. Here, we describe a case of CCSK and present immunohistochemical studies of its vasculature.
|Number of pages||6|
|Journal||Journal of Pediatric Surgery|
|Publication status||Published - 2009 Oct|
- Clear cell sarcoma of the kidney
- Vascular endothelial growth factor
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health