Very fast reactions and extreme conditions

H. Kim, J. Yoshida

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)


Microreaction technology represents a powerful and unique tool for the control of extremely fast reactions and reactions under extreme conditions. In this chapter, fast flow reactions such as Swern–Moffatt oxidations, diisobutylaluminum hydride reductions, reactions involving organolithiums and organomagnesiums, and Friedel–Crafts alkylations are presented. Moreover, this chapter also covers examples of reactions performed under extreme reaction conditions of high temperature and high pressure, which cannot be easily conducted in flasks.

Original languageEnglish
Title of host publicationScience of Synthesis
EditorsM.C. Bagley
PublisherGeorg Thieme Verlag
Number of pages20
ISBN (Electronic)9783132423312
Publication statusPublished - 2018

Publication series

NameScience of Synthesis
ISSN (Print)2510-5469
ISSN (Electronic)2566-7297

Bibliographical note

Publisher Copyright:
© 2018 Georg Thieme Verlag. All rights reserved.


  • Extreme conditions
  • Fast reactions
  • Flash chemistry
  • Flow chemistry
  • High pressure
  • High temperature
  • Microreactors
  • Organolithiums
  • Unstable intermediates

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry


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