Vinyl sulfone synthesisviacopper-catalyzed three-component decarboxylative addition

Seunghwan An, Kwang Ho Song, Sunwoo Lee

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


The synthesis of vinyl sulfone derivativesviathe reaction of arylpropiolic acids, K2S2O5, and aryl boronic acids is reported. The CuBr2/1,10-phenanthroline catalytic system in the presence of acetic acid provides the desired vinyl sulfones in moderate to good yield. Furthermore, the methodology features excellent functional group tolerance.

Original languageEnglish
Pages (from-to)7827-7831
Number of pages5
JournalOrganic and Biomolecular Chemistry
Issue number36
Publication statusPublished - 2021 Sept 28

Bibliographical note

Funding Information:
This research was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (NRF-2021R1A2C1005169). Spectral and HRMS data were obtained at the Korea Basic Science Institute, Gwangju center and Daegu center.

Publisher Copyright:
© The Royal Society of Chemistry 2021.

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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