Vinyl sulfone synthesisviacopper-catalyzed three-component decarboxylative addition

Seunghwan An; Kwang Ho Song; Sunwoo Lee

doi:10.1039/d1ob01435h

Vinyl sulfone synthesisviacopper-catalyzed three-component decarboxylative addition

Seunghwan An, Kwang Ho Song, Sunwoo Lee

Department of Chemical and Biological Engineering

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The synthesis of vinyl sulfone derivativesviathe reaction of arylpropiolic acids, K₂S₂O₅, and aryl boronic acids is reported. The CuBr₂/1,10-phenanthroline catalytic system in the presence of acetic acid provides the desired vinyl sulfones in moderate to good yield. Furthermore, the methodology features excellent functional group tolerance.

Original language	English
Pages (from-to)	7827-7831
Number of pages	5
Journal	Organic and Biomolecular Chemistry
Volume	19
Issue number	36
DOIs	https://doi.org/10.1039/d1ob01435h
Publication status	Published - 2021 Sept 28

Bibliographical note

Funding Information:
This research was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (NRF-2021R1A2C1005169). Spectral and HRMS data were obtained at the Korea Basic Science Institute, Gwangju center and Daegu center.

Publisher Copyright:
© The Royal Society of Chemistry 2021.

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/d1ob01435h

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title = "Vinyl sulfone synthesisviacopper-catalyzed three-component decarboxylative addition",

abstract = "The synthesis of vinyl sulfone derivativesviathe reaction of arylpropiolic acids, K2S2O5, and aryl boronic acids is reported. The CuBr2/1,10-phenanthroline catalytic system in the presence of acetic acid provides the desired vinyl sulfones in moderate to good yield. Furthermore, the methodology features excellent functional group tolerance.",

author = "Seunghwan An and Song, {Kwang Ho} and Sunwoo Lee",

note = "Funding Information: This research was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (NRF-2021R1A2C1005169). Spectral and HRMS data were obtained at the Korea Basic Science Institute, Gwangju center and Daegu center. Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2021.",

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doi = "10.1039/d1ob01435h",

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T1 - Vinyl sulfone synthesisviacopper-catalyzed three-component decarboxylative addition

AU - An, Seunghwan

AU - Song, Kwang Ho

AU - Lee, Sunwoo

N1 - Funding Information: This research was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (NRF-2021R1A2C1005169). Spectral and HRMS data were obtained at the Korea Basic Science Institute, Gwangju center and Daegu center. Publisher Copyright: © The Royal Society of Chemistry 2021.

PY - 2021/9/28

Y1 - 2021/9/28

N2 - The synthesis of vinyl sulfone derivativesviathe reaction of arylpropiolic acids, K2S2O5, and aryl boronic acids is reported. The CuBr2/1,10-phenanthroline catalytic system in the presence of acetic acid provides the desired vinyl sulfones in moderate to good yield. Furthermore, the methodology features excellent functional group tolerance.

AB - The synthesis of vinyl sulfone derivativesviathe reaction of arylpropiolic acids, K2S2O5, and aryl boronic acids is reported. The CuBr2/1,10-phenanthroline catalytic system in the presence of acetic acid provides the desired vinyl sulfones in moderate to good yield. Furthermore, the methodology features excellent functional group tolerance.

UR - http://www.scopus.com/inward/record.url?scp=85115665142&partnerID=8YFLogxK

U2 - 10.1039/d1ob01435h

DO - 10.1039/d1ob01435h

M3 - Article

C2 - 34549236

AN - SCOPUS:85115665142

SN - 1477-0520

VL - 19

SP - 7827

EP - 7831

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 36

ER -

Vinyl sulfone synthesisviacopper-catalyzed three-component decarboxylative addition

Abstract

Bibliographical note

ASJC Scopus subject areas

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