Weight reduction effects of yeast hydrolysate below 10kDa on obese young women

We investigated the antiobesity effects of yeast hydrolysate below 10kDa on obese young women for the 4 weeks to assess its possibility as a dietary supplement. Subjects were randomly assigned to the placebo group (n=10) and yeast hydrolysate below 10kDa 1g/day (YH) group (n=10). The results showed body weight was lost significantly (P<0.05) in the YH group (1.68kg) compared with placebo group (0.71kg). And the percent ideal body weight (PIBW) and body mass index (BMI) of the YH group (PIBW: 3.04%; BMI: 0.65kg/m2) were decreased significantly (P<0.05) compared with placebo group (PIBW: 1.26%; BMI: 0.27kg/m2). The reductions of fat mass, percent body fat, body circumference and skinfold thickness also were slightly higher in the YH group than placebo group, however, the significant effects in these variables were not observed. PRACTICAL APPLICATIONS: The limited long-term efficacy of conventional weight management (dietary intervention, physical activity and behavioral therapy) has lead to the development of alternative weight reduction strategies. Alternative therapies such as the use of natural supplements are beginning to form a large and growing market. In order to provide new discoveries and solutions related to natural supplements, we have turned to yeast, a microorganism that mankind has long made use of. The development of dietary supplement using yeast is very valuable for fields related to antiobesity. This report may give useful information about the use of yeast hydrolysate below 10kDa as a weight-loss supplement.