Years from menopause-to-surgery is a major factor in the post-operative subjective outcome for pelvic organ prolapse

Introduction and hypothesis: The purpose of the current study was to determine the main factors associated with post-operative subjective outcome in post-menopausal patients with pelvic organ prolapse. Methods: Ninety-four women were selected among patients who underwent surgery for grade 3 or 4 prolapse. The outcome was evaluated by the Patient Global Impression of Improvement (PGI-I) scale. Multivariate ordinal regression analysis was performed. Results: The number of patients with improvement (1 or 2 on the PGI-I scale) was 88 (93.7%). Age and years from menopause-to-surgery were negatively (β=-0.16, P=0.01) and positively (β=0.14, P=0.01) associated with the PGI-I scale. The aging effect was lost after adjusting for prolapse grade. Conclusion: The greater the number of years from menopause-to-pelvic organ prolapse surgery, the less satisfied were the patients. The association between older patients and greater satisfaction appears to be a confounding effect of prolapse grade.