Yeast hydrolysate as a functional anti-obesity ingredient: Appetite suppressive effects of yeast hydrolysate in food-deprived mice

Ki Bae Hong; Eun Young Jung; Jae Hwan Kim; Un Jae Chang; Hyung Joo Suh

Yeast hydrolysate as a functional anti-obesity ingredient: Appetite suppressive effects of yeast hydrolysate in food-deprived mice

Ki Bae Hong, Eun Young Jung, Jae Hwan Kim, Un Jae Chang, Hyung Joo Suh

Research output: Contribution to journal › Article › peer-review

Abstract

The aim of this study was to investigate the appetite suppression effects of yeast hydrolysate (YH). Male ICR mice (8 weeks old) were randomly divided into three groups (n=6) as follows: Saline group, which was treated with saline (control); YH0.5 group, which was treated with YH 0.5 g/kg BW; and YH1 group, which was treated with YH 1 g/kg BW. At the beginning of the experiment, the mice were intraperitoneally (IP) injected with either saline or YH. The results showed that YH caused a significant attenuation of food intake in fasted mice (p<0.05) and significantly lowered serum ghrelin levels (YH0.5, 2002.22 pg/mL; YH1, 2337.65 pg/mL vs. Saline, 3363.61 pg/mL, p<0.05). This study indicates that the appetite suppression effects of YH is likely explained by the attenuation of ghrelin.

Original language	English
Pages (from-to)	262-264
Number of pages	3
Journal	Progress in Nutrition
Volume	17
Issue number	3
Publication status	Published - 2015 Nov 30

Bibliographical note

Publisher Copyright:
© Mattioli 1885

Keywords

Appetite
Ghrelin
Obesity
Yeast hydrolysate

ASJC Scopus subject areas

Food Science
Nutrition and Dietetics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Yeast hydrolysate as a functional anti-obesity ingredient: Appetite suppressive effects of yeast hydrolysate in food-deprived mice",

abstract = "The aim of this study was to investigate the appetite suppression effects of yeast hydrolysate (YH). Male ICR mice (8 weeks old) were randomly divided into three groups (n=6) as follows: Saline group, which was treated with saline (control); YH0.5 group, which was treated with YH 0.5 g/kg BW; and YH1 group, which was treated with YH 1 g/kg BW. At the beginning of the experiment, the mice were intraperitoneally (IP) injected with either saline or YH. The results showed that YH caused a significant attenuation of food intake in fasted mice (p<0.05) and significantly lowered serum ghrelin levels (YH0.5, 2002.22 pg/mL; YH1, 2337.65 pg/mL vs. Saline, 3363.61 pg/mL, p<0.05). This study indicates that the appetite suppression effects of YH is likely explained by the attenuation of ghrelin.",

keywords = "Appetite, Ghrelin, Obesity, Yeast hydrolysate",

author = "Hong, {Ki Bae} and Jung, {Eun Young} and Kim, {Jae Hwan} and Chang, {Un Jae} and Suh, {Hyung Joo}",

note = "Publisher Copyright: {\textcopyright} Mattioli 1885",

year = "2015",

month = nov,

day = "30",

language = "English",

volume = "17",

pages = "262--264",

journal = "Progress in Nutrition",

issn = "1129-8723",

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T1 - Yeast hydrolysate as a functional anti-obesity ingredient

T2 - Appetite suppressive effects of yeast hydrolysate in food-deprived mice

AU - Hong, Ki Bae

AU - Jung, Eun Young

AU - Kim, Jae Hwan

AU - Chang, Un Jae

AU - Suh, Hyung Joo

PY - 2015/11/30

Y1 - 2015/11/30

N2 - The aim of this study was to investigate the appetite suppression effects of yeast hydrolysate (YH). Male ICR mice (8 weeks old) were randomly divided into three groups (n=6) as follows: Saline group, which was treated with saline (control); YH0.5 group, which was treated with YH 0.5 g/kg BW; and YH1 group, which was treated with YH 1 g/kg BW. At the beginning of the experiment, the mice were intraperitoneally (IP) injected with either saline or YH. The results showed that YH caused a significant attenuation of food intake in fasted mice (p<0.05) and significantly lowered serum ghrelin levels (YH0.5, 2002.22 pg/mL; YH1, 2337.65 pg/mL vs. Saline, 3363.61 pg/mL, p<0.05). This study indicates that the appetite suppression effects of YH is likely explained by the attenuation of ghrelin.

AB - The aim of this study was to investigate the appetite suppression effects of yeast hydrolysate (YH). Male ICR mice (8 weeks old) were randomly divided into three groups (n=6) as follows: Saline group, which was treated with saline (control); YH0.5 group, which was treated with YH 0.5 g/kg BW; and YH1 group, which was treated with YH 1 g/kg BW. At the beginning of the experiment, the mice were intraperitoneally (IP) injected with either saline or YH. The results showed that YH caused a significant attenuation of food intake in fasted mice (p<0.05) and significantly lowered serum ghrelin levels (YH0.5, 2002.22 pg/mL; YH1, 2337.65 pg/mL vs. Saline, 3363.61 pg/mL, p<0.05). This study indicates that the appetite suppression effects of YH is likely explained by the attenuation of ghrelin.

KW - Appetite

KW - Ghrelin

KW - Obesity

KW - Yeast hydrolysate

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SN - 1129-8723

VL - 17

SP - 262

EP - 264

JO - Progress in Nutrition

JF - Progress in Nutrition

IS - 3

ER -

Yeast hydrolysate as a functional anti-obesity ingredient: Appetite suppressive effects of yeast hydrolysate in food-deprived mice

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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