Abstract
The purpose of this study was to assess the antiobesity effect of the yeast hydrolysate (DNF) on the body weight, body fat and plasma lipids levels of high-fat fed rats. The weight gain of the HF (high fat diet) (162.58 ± 6.68 g) was significantly (p < 0.05) greater than that of DNF-1, DNF-2, (high fat diet with DNF of 0.5 and 1.0 g/kg body weight, respectively) and control groups (143.19 ± 7.33 g, 139.20 ± 8.36 g, 130.23 ± 8.02 g, respectively). The wet weight of the epididymal fat and the perirenal fat pads of the DNF-1, DNF-2 and control groups were reduced significantly (p < 0.05). A significant (p < 0.05) increase of HDL-cholesterol level of the DNF-2 and control groups was observed. However, there was no significant difference between DNF-1 and DNF-2. It was also found that the triacylglycerol (TG) levels decreased significantly (p < 0.05) in the DNF-2 group from that of the HF, but there was no significant (p < 0.05) difference between DNF-1 and DNF-2.
Original language | English |
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Pages (from-to) | 950-953 |
Number of pages | 4 |
Journal | Phytotherapy Research |
Volume | 18 |
Issue number | 11 |
DOIs | |
Publication status | Published - 2004 Nov |
Keywords
- Hypolipidaemic effect
- Triacyglycerol
- Yeast hydrolysate
ASJC Scopus subject areas
- Pharmacology