Yeast hydrolysate reduces body fat of dietary obese rats

K. M. Kim; U. J. Chang; D. H. Kang; J. M. Kim; Y. M. Choi; H. J. Suh

doi:10.1002/ptr.1582

Yeast hydrolysate reduces body fat of dietary obese rats

K. M. Kim, U. J. Chang, D. H. Kang, J. M. Kim, Y. M. Choi, H. J. Suh

School of Biosystem and Biomedical Science

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

The purpose of this study was to assess the antiobesity effect of the yeast hydrolysate (DNF) on the body weight, body fat and plasma lipids levels of high-fat fed rats. The weight gain of the HF (high fat diet) (162.58 ± 6.68 g) was significantly (p < 0.05) greater than that of DNF-1, DNF-2, (high fat diet with DNF of 0.5 and 1.0 g/kg body weight, respectively) and control groups (143.19 ± 7.33 g, 139.20 ± 8.36 g, 130.23 ± 8.02 g, respectively). The wet weight of the epididymal fat and the perirenal fat pads of the DNF-1, DNF-2 and control groups were reduced significantly (p < 0.05). A significant (p < 0.05) increase of HDL-cholesterol level of the DNF-2 and control groups was observed. However, there was no significant difference between DNF-1 and DNF-2. It was also found that the triacylglycerol (TG) levels decreased significantly (p < 0.05) in the DNF-2 group from that of the HF, but there was no significant (p < 0.05) difference between DNF-1 and DNF-2.

Original language	English
Pages (from-to)	950-953
Number of pages	4
Journal	Phytotherapy Research
Volume	18
Issue number	11
DOIs	https://doi.org/10.1002/ptr.1582
Publication status	Published - 2004 Nov

Keywords

Hypolipidaemic effect
Triacyglycerol
Yeast hydrolysate

ASJC Scopus subject areas

Pharmacology

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10.1002/ptr.1582

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title = "Yeast hydrolysate reduces body fat of dietary obese rats",

abstract = "The purpose of this study was to assess the antiobesity effect of the yeast hydrolysate (DNF) on the body weight, body fat and plasma lipids levels of high-fat fed rats. The weight gain of the HF (high fat diet) (162.58 ± 6.68 g) was significantly (p < 0.05) greater than that of DNF-1, DNF-2, (high fat diet with DNF of 0.5 and 1.0 g/kg body weight, respectively) and control groups (143.19 ± 7.33 g, 139.20 ± 8.36 g, 130.23 ± 8.02 g, respectively). The wet weight of the epididymal fat and the perirenal fat pads of the DNF-1, DNF-2 and control groups were reduced significantly (p < 0.05). A significant (p < 0.05) increase of HDL-cholesterol level of the DNF-2 and control groups was observed. However, there was no significant difference between DNF-1 and DNF-2. It was also found that the triacylglycerol (TG) levels decreased significantly (p < 0.05) in the DNF-2 group from that of the HF, but there was no significant (p < 0.05) difference between DNF-1 and DNF-2.",

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AU - Chang, U. J.

AU - Kang, D. H.

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AU - Choi, Y. M.

AU - Suh, H. J.

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N2 - The purpose of this study was to assess the antiobesity effect of the yeast hydrolysate (DNF) on the body weight, body fat and plasma lipids levels of high-fat fed rats. The weight gain of the HF (high fat diet) (162.58 ± 6.68 g) was significantly (p < 0.05) greater than that of DNF-1, DNF-2, (high fat diet with DNF of 0.5 and 1.0 g/kg body weight, respectively) and control groups (143.19 ± 7.33 g, 139.20 ± 8.36 g, 130.23 ± 8.02 g, respectively). The wet weight of the epididymal fat and the perirenal fat pads of the DNF-1, DNF-2 and control groups were reduced significantly (p < 0.05). A significant (p < 0.05) increase of HDL-cholesterol level of the DNF-2 and control groups was observed. However, there was no significant difference between DNF-1 and DNF-2. It was also found that the triacylglycerol (TG) levels decreased significantly (p < 0.05) in the DNF-2 group from that of the HF, but there was no significant (p < 0.05) difference between DNF-1 and DNF-2.

AB - The purpose of this study was to assess the antiobesity effect of the yeast hydrolysate (DNF) on the body weight, body fat and plasma lipids levels of high-fat fed rats. The weight gain of the HF (high fat diet) (162.58 ± 6.68 g) was significantly (p < 0.05) greater than that of DNF-1, DNF-2, (high fat diet with DNF of 0.5 and 1.0 g/kg body weight, respectively) and control groups (143.19 ± 7.33 g, 139.20 ± 8.36 g, 130.23 ± 8.02 g, respectively). The wet weight of the epididymal fat and the perirenal fat pads of the DNF-1, DNF-2 and control groups were reduced significantly (p < 0.05). A significant (p < 0.05) increase of HDL-cholesterol level of the DNF-2 and control groups was observed. However, there was no significant difference between DNF-1 and DNF-2. It was also found that the triacylglycerol (TG) levels decreased significantly (p < 0.05) in the DNF-2 group from that of the HF, but there was no significant (p < 0.05) difference between DNF-1 and DNF-2.

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Yeast hydrolysate reduces body fat of dietary obese rats

Abstract

Keywords

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