Abstract
Surface biomaterials and topography of extracellular matrices (ECMs) is critical for the culture of various cells and modern tissue engineering. However, the potential of ECMs are relatively not much focused as an important factor in those purposes. Actually, the very first cell differentiation at the transition from an eight-cell embryo to a blastocyst occurs within an ECM called the zona pellucida during early mammalian embryonic development. Therefore the zona pellucida can be considered to be one of the best candidate ECMs for cell cultures, if it could be clearly separated. In addition, the natural three dimensional spherical structure of the zona pellucida would also be effective for embryoid body (EB) formation. However, to obtain the zona pellucida keeping its original spherical form without splitting of the membrane is quite difficult due to its small size (
| Original language | English |
|---|---|
| Title of host publication | IFMBE Proceedings |
| Publisher | Springer Verlag |
| Pages | 3379-3381 |
| Number of pages | 3 |
| Volume | 14 |
| Edition | 1 |
| Publication status | Published - 2007 |
| Event | 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of Duration: 2006 Aug 27 → 2006 Sept 1 |
Other
| Other | 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 |
|---|---|
| Country/Territory | Korea, Republic of |
| City | Seoul |
| Period | 06/8/27 → 06/9/1 |
Keywords
- Cell culture
- Chorion
- Extracellular matrix
ASJC Scopus subject areas
- Biomedical Engineering
- Bioengineering