Zebrafish chorion as an extracellular matrix for cell culture

Jin Woo Lee, Dae Seok Na, Byeong Kwon Ju

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)


Surface biomaterials and topography of extracellular matrices (ECMs) is critical for the culture of various cells and modern tissue engineering. However, the potential of ECMs are relatively not much focused as an important factor in those purposes. Actually, the very first cell differentiation at the transition from an eight-cell embryo to a blastocyst occurs within an ECM called the zona pellucida during early mammalian embryonic development. Therefore the zona pellucida can be considered to be one of the best candidate ECMs for cell cultures, if it could be clearly separated. In addition, the natural three dimensional spherical structure of the zona pellucida would also be effective for embryoid body (EB) formation. However, to obtain the zona pellucida keeping its original spherical form without splitting of the membrane is quite difficult due to its small size (

Original languageEnglish
Title of host publicationIFMBE Proceedings
PublisherSpringer Verlag
Number of pages3
Publication statusPublished - 2007
Event10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of
Duration: 2006 Aug 272006 Sept 1


Other10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
Country/TerritoryKorea, Republic of


  • Cell culture
  • Chorion
  • Extracellular matrix

ASJC Scopus subject areas

  • Biomedical Engineering
  • Bioengineering


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