Abstract
We report on the fabrication of electrical biosensors based on functionalized ZnO nanorod surfaces with biotin for highly sensitive detection of biological molecules. Due to the clean interface and easy surface modification, the ZnO nanorod sensors can easily detect streptavidin binding down to a concentration of 25 nM, which is more sensitive than previously reported one-dimensional (ID) nanostructure electrical biosensors. In addition, the unique device structure with a micrometer-scale hole at the center of the ZnO nanorod's conducting channel reduces the leakage current from the aqueous solution, hence enhancing device sensitivity. Moreover, ZnO nanorod field-effect-transistor (FET) sensors may open up opportunities to create many other oxide nanorod electrical sensors for highly sensitive and selective real-time detection of a wide variety of biomolecules.
Original language | English |
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Pages (from-to) | 1635-1639 |
Number of pages | 5 |
Journal | Journal of the Korean Physical Society |
Volume | 49 |
Issue number | 4 |
Publication status | Published - 2006 Oct |
Externally published | Yes |
Keywords
- Biosensor
- Field effect transistor (FET)
- Nanorod
- ZnO
ASJC Scopus subject areas
- General Physics and Astronomy